General pharmacology

Drugs undergoing complete First pass metabolism

Submitted by Nishanth_koda on Sun, 03/08/2008 - 15:38
in

Drugs undergoing complete first pass metabolism when taken orally

'F I L T Hy'

  • First pass metabolism
  • Isoprenaline
  • Lignocaine
  • Testosterone
  • Hydrocortisone

4.5
  • 172 reads

Enzyme inducers

Submitted by sandip_vj on Sun, 21/06/2009 - 16:11
in

 ' P RAGA ' 

  • Phenylbutazone
  • Anticonvulsants
  • Rifampicin
  • Griseofulvin
  • Alcohol
3

Enzyme inhibitors

Submitted by sandip_vj on Sun, 21/06/2009 - 16:07
in

 ' COMIC CASE '

  • Cimetidine
  • Omeprazole
  • Metronidazole
  • Isoniazid
  • Chloramphenicol
  • Ciprofloxacin
  • Allopurinol
  • Sulphonamides
  • Erythromycin

 

3

Drugs metabolized by acetylation

Submitted by Silverflame on Fri, 02/01/2009 - 21:05
in

' SHIP'

  • Sulfonamides including dapsone
  • Hydralazine
  • Isoniazid (INH)
  • Procainamide

Acetylator polymorphism:Some individuals are slow acetylators and some are fast acetylators.The drugs metabolized by acetylation may become ineffective in fast acetylators and cause toxicity in slow acetylators.
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