Histology

Mallory bodies: Conditions in which they can be seen

Submitted by neema_neetha on Wed, 04/03/2009 - 22:28
in

"Alcoholic Bill Calls Tumor  Wilson"

  • Alcoholic hepatitis
  • Primary biliary cirrhosis
  • Cholestatic syndromes
  • Tumor- hepatocellular carcinoma
  • Wilson's disease
Named after the American pathologist Frank Burr Mallory and also known as alcoholic hyaline, mallory body is an eosinophilic intracytoplasmic inclusion body found in the liver parenchyma in a variety of liver diseases. It consists of a perinuclear aggregate of filamentous material that mostly consists of intermediate cytokeratin filaments.Mallory bodies primarily contain keratin-8 (KRT8) and keratin-18 (KRT18).
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