Diabetes Mellitus: Oral Hypoglycaemic Agents

Submitted by otonglotime on Sun, 24/01/2010 - 17:42
in

 Oral hypoglycaemic drugs used in management of Diabetes Mellitus 

" B.A.S.T.I.P "

  • Biguanides - Metmorfin
  • Alpha-glucosidase inhibitors - Acarbose
  • Sulphonylureas - Tobultamide, Glipizide
  • Thiazolidinediones - Rosiglitazone
  • Incretin Mimetics - Liraglutide
  • Prandial Glucose Regulators - Meglitinide, Repaglinide

 

3.5

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image Incretin mimetics are derivatives of GLP-1 (glucagon-like peptide) which stimulate insulin secretion, supress glucagon secretion, delay gastric emptying, decrease appetite and promote weight loss.
image Prandial Glucose Regulators are amino acid derivatives and stimulate endogenous insulin secretion. Ideally, they are to be taken immedaitely before food.

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